Checkpoint blockade in cancer immunotherapy [electronic resource] / James P. Allison.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (72 min.) : color, sound)Subject(s): Antibodies, Monoclonal -- therapeutic use | Immunotherapy | Neoplasms -- therapyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Activation of naive T-cells -- CD28 and CTLA-4 -- Differential regulation of T-cell responses -- Responding repertoire -- Biological role of CTLA-4 -- Tumor-specific immune responses -- Treg activity -- CTLA-4/GVax -- Immunotherapies -- Conventional therapies -- Ipilumumab -- Clinical studies: melanoma -- Reversible immune mediated toxicity.
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Mode of access: World Wide Web.