Genomic insights into gene regulation by cohesin [electronic resource] / Dale Dorsett.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Epigenetics, chromatin, transcription and cancer: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (60 min.) : color, sound)Subject(s): Chromosomal proteins | Gene expression | Genetic regulation | Genetic transcription | Genomes | Cell Cycle Proteins -- metabolism | Chromosomal Proteins, Non-Histone -- metabolism | De Lange Syndrome | Drosophila -- genetics | Gene Expression Regulation, Developmental | Genome, Human | Polycomb-Group Proteins | Regulatory Sequences, Nucleic Acid | Transcription, GeneticOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Cohesin regulates gene expression and development in Drosophila and Humans -- Cohesin binds a subset of active genes at transcription start sites -- Cohesin directly regulates many genes Important for growth and development -- Cohesin cooperates with polycomb epigenetic silencing complexes to restrain gene expression -- Cohesin selectively binds genes with paused RNA Polymerase and regulates transition to transcriptional elongation -- Questions regarding the roles of cohesin in gene regulation and development and relevance to human disease.
Access restricted to subscribers.
Mode of access: World Wide Web.