Congenital syndromes of pain and painlessness [electronic resource] / Geoff Woods.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Molecular genetics of human disease: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (57 min.) : color, sound)Subject(s): Congenital insensitivity to pain | Genetic disorders | Pain | Dysautonomia, Familial | Erythromelalgia | Hereditary Sensory and Autonomic Neuropathies | Pain Insensitivity, Congenital | Pain | Paroxysmal Extreme Pain DisorderOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: What is pain? -- How much pain is someone suffering? -- What is the use of pain? -- Pain pathways -- Types of pain (Nociceptive, Inflammatory, Neuropathic, mixed) -- Primary erythromelalgia -- Mutations in SCN9A cause erythromelalgia -- Voltage-gated ion channels -- Paroxysmal extreme pain disorder (familial rectal pain) -- Mutations in SCN9A cause PEPD -- Congenital insensitivity to pain -- SCN9A gene map -- Electrical activity of wild type versus mutant constructs -- Low-copy number vector = pcDNA3JC -- Exon 6 splice variants -- Neuropathies HSANs -- Rita Levi Montalcini -- TRKA signalling -- Hereditary autonomic and sensory neuropathy type 4 (HSAN4) -- HSAN5 -- NGFB -- Familial dysautonomia -- Treatment of pain -- Mendelian disorders of pain.
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Mode of access: World Wide Web.