Segregation analysis [electronic resource] / Chris Cannings & Dawn Teare.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetic epidemiology I : fundamentals, theory, practice and latest developments: Publisher: London : Henry Stewart Talks, 2004Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Genetic Predisposition to Disease -- epidemiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Components of segregation analysis -- Maximum likelihood models -- Peeling and MCMC -- Estimating the segregation proportion -- Ascertainment/sampling bias -- Ascertainment correction -- Segregation analysis for quantitative traits -- Polygenic models -- Heritability -- Components of variance -- Genetic variance: additive and dominance -- Epistatic variance -- Analysis of covariance -- Mixed models -- Liability and threshold models -- The hypergeometric polygenic model -- Regressive models -- Penetrance functions -- Survival models -- Computer packages.
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Mode of access: World Wide Web.