Adjusting for population structure in genetic association studies [electronic resource] / David Balding.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetic epidemiology II : latest developments: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (50 min.) : color, sound)Subject(s): Genetic Predisposition to Disease -- epidemiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Effect of population structure in generating spurious associations -- Cause of problem is confounded by pedigree -- Pre-2006 solutions: design based (TDT), genomic control, structured association -- New solutions in 2006: null markers as regression covariates, principal components as regression covariates, linear mixed models using pairwise kinships.
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Mode of access: World Wide Web.