Self-splicing intron RNAs [electronic resource] : ribozymes, parasites and agents of genomic change / Anna Marie Pyle.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. From DNA to proteins : the multiple levels of regulation: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (60 min.) : color, sound)Subject(s): Introns | Protein-protein interactions | RNA splicing | Evolution, Molecular | Introns -- genetics | Introns -- physiology | RNA Splicing | RNA -- chemistry | RNA -- metabolism | RNA, Catalytic | Spliceosomes -- metabolismOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Different classes of introns -- Autocatalytic group I and group II introns -- Discovery of self-splicing -- Converting a self-splicing RNA into a multiple-turnover enzyme -- The "tetrahymena ribozyme" and discovery of RNA catalysis -- New insights into molecular recognition of RNA -- Group I intron structure and catalytic mechanism -- Group I intron applications -- Group II introns and the big picture -- Discovery of self-splicing by group II introns -- Chemical mechanism of group II intron reactions -- Catalytic engines for driving eukaryotic evolution -- Explaining specificity of group II ribozymes -- Group II intron ribozymes as model systems for RNA folding -- Group II ribozymes as model systems for RNA tertiary structure -- Nucleotide analog interference mapping -- Current map of important atoms -- Nucleotide analog interference suppression -- Lambda-lambda interaction -- 3D model of ai5gamma intron -- Group II introns as tools and therapeutics.
Access restricted to subscribers.
Mode of access: World Wide Web.