Population-specific evolution of natural killer cell diversity [electronic resource] / Paul J. Norman.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2011Description: 1 online resource (1 streaming video file (32 min.) : color, sound)Subject(s): Human genetics -- Variation | Killer cells | Population genetics | Evolution, Molecular | Genetic Variation -- genetics | Genetics, Population | Humans | Killer CellsOnline resources: Click here to access online Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: NK cell Diversity; KIR and HLA -- Genetic variety of human immune systems -- Natural killer (NK) cell functions -- HLA and KIR polymorphism -- Genetic association with infectious disease -- Pregnancy syndromes -- Maintenance of diversity in populations -- KIR haplotypes, balancing selection, population bottlenecks, human population diversity -- Natural selection and functional variation, cell-free assays, allelic variants with altered specificities -- Extent of Diversity in Populations -- HLA/KIR compound genotypes and immune identity -- Distribution of viable KIR/HLA interactions -- KIR/HLA in Ancient Humans -- Virtual HLA/KIR genotype of Denisova and Neanderthal -- Distribution of ancient human KIR/HLA alleles in modern humans.
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Mode of access: World Wide Web.