Skin epigenetics [electronic resource] : how chromatin regulators orchestrate skin functions / Vladimir Botchkarev.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Skin biology: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (33 min.) : color, sound)Subject(s): Chromatin | Epidermis -- Molecular aspects | Epigenesis | Skin -- Molecular aspects | Cell Differentiation | Chromatin Assembly and Disassembly -- genetics | Chromatin -- metabolism | DNA Methylation | Epidermis -- growth & development | Epigenesis, Genetic -- physiology | Gene Expression Regulation, Developmental | Keratinocytes | Protein Processing, Post-Translational | Skin Physiological Phenomena | Skin -- growth & development | Transcription FactorsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Skin structure, functions and development -- Molecular control of cell differentiation -- What is epigenetics? -- What controls variability of skin phenotypes? -- Genes encoding keratinocyte-specific proteins -- Molecular signature of epidermal layers -- Levels of epigenetic regulation -- DNA methylation and hydroxymethylation -- DNA methylation influence on the epidermis -- Post-translational histone/covalent modifications -- Histone acetylation/de-acetylation -- Polycomb-repressive complex -- Polycomb and Trithorax play antagonistic roles -- ATP-dependent chromatin remodeling -- Non-coding RNA-dependent mechanisms -- Nucleus: storage, replication of genetic material -- Topological gene interactomes -- Morphogenesis of the epidermis -- Epidermal differentiation complex -- EDC and Lor relocation to nuclear interior -- p63 and Brg1 ablation results in retention of EDC -- Genome organizer AT-rich binding Satb1 protein -- Transcription factor and epigenetic mechanisms -- Future directions of epigenetic research.
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Mode of access: World Wide Web.