Evaluation of the adult nervous system in preclinical studies [electronic resource] / Mark T. Butt.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Non-clinical testing for toxicity of pharmaceuticals: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (42 min.) : color, sound)Subject(s): Drug Toxicity | Toxicity TestsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchonized narration.
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Contents: Brain is a heterogeneous tissue: you must look at many sections -- Different toxicants affect different areas -- Timing is important but most cell death occurs early (1 to 4 days) -- Appropriate fixation is crucial -- Appropriate staining methods are necessary to detect changes in various cell types (neurons, glial cells).
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Mode of access: World Wide Web.