Antisense oligonucleotides [electronic resource] : the promise and the problems / Kendall S. Frazier.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection: Publisher: London : Henry Stewart Talks, 2015Description: 1 online resource (1 streaming video file (45 min.) : color, sound)Subject(s): Antisense nucleic acids | Drug development | Toxicity testing | Drug Discovery -- methods | Oligonucleotides, Antisense -- adverse effects | Oligonucleotides, Antisense -- therapeutic use | Oligonucleotides, Antisense -- toxicity | Patient Safety | Toxicity TestsOnline resources: Click here to access online Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Antisense oligonucleotide (ASOs) therapies -- Screening strategies for drug candidates -- Locked nucleic acid (LNA) gapmers -- Understanding off-target effects (OTEs) -- Mechanisms of ASO toxicity and clinical relevance -- New targets/delivery systems under development.
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Mode of access: World Wide Web.