Key drug discovery challenges in cardiovascular medicine [electronic resource] / Daniel I. Swerdlow and Michael V. Holmes.

By: Swerdlow, Daniel I [spk]Contributor(s): Holmes, Michael V. (University of Pennsylvania, USA) [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Genetics of cardiovascular disease: ; Henry Stewart talksBiomedical & life sciences collection. Small molecule drug discovery: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (31 min.) : color, sound)Subject(s): Cardiovascular agents | Cardiovascular system -- Diseases -- Chemotherapy | Drug development | Drugs -- Research | Pharmacogenetics | Cardiovascular Agents -- therapeutic use | Cardiovascular Diseases -- drug therapy | Drug Discovery -- methods | Precision MedicineOnline resources: Click here to access online | Series (Genetics of cardiovascular disease) | Series (Small molecule drug discovery)
Contents:
Contents: Conventional therapeutic targets in CVD -- Identifying new targets (GWAS and association analysis) -- Validating new targets (Mendelian randomisation; IL6R, CHD and tocilizumab; sPLA2 inhibition and CHD prevention) -- Avoiding adverse effects (The ILLUMINATE trial, Torcetrapib and blood pressure) -- Making better use of existing drugs (Pharmacogenetics of Clopidogrel and CYP2C19) -- New approaches & drug development.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: Conventional therapeutic targets in CVD -- Identifying new targets (GWAS and association analysis) -- Validating new targets (Mendelian randomisation; IL6R, CHD and tocilizumab; sPLA2 inhibition and CHD prevention) -- Avoiding adverse effects (The ILLUMINATE trial, Torcetrapib and blood pressure) -- Making better use of existing drugs (Pharmacogenetics of Clopidogrel and CYP2C19) -- New approaches & drug development.

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