Historical and ethical issues in trial design [electronic resource] / J. Rosser Matthews.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Design and analysis of randomized clinical trials : design, analysis & theory: Publisher: London : Henry Stewart Talks, 2018Description: 1 online resource (1 streaming video file (43 min.) : color, sound)Subject(s): Clinical trials -- Design | Clinical trials -- History | Clinical trials -- Moral and ethical aspects | Control Groups | Ethical Theory | Informed Consent | Pharmacology, Clinical -- ethics | Randomized Controlled Trials as Topic -- ethics | Randomized Controlled Trials as Topic -- history | Research Design | StreptomycinOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Updated version of a talk first published in 2007.
Contents: Historical antecedents to the clinical trial -- Pharmacology & mathematical statistics as key for clinical trials -- Shortage of streptomycin during WWII & use of control groups -- Unethical research studies & informed consent by study subjects -- Withholding a potentially useful therapy -- Letting chance determine patient assignment -- Advancing scientific knowledge without reducing study participants to a means to an end -- General ethical frameworks of Utilitarianism & Kantianism -- Eight factors to be considered in designing ethical and scientific studies.
Access restricted to subscribers.
Mode of access: World Wide Web.