Prion-like propagation of Parkinson's disease [electronic resource] / Patrik Brundin.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Parkinson's disease: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (61 min.) : color, sound)Subject(s): Lewy body dementia | Parkinson's disease -- Pathophysiology | Parkinson's disease -- Treatment | Prion diseases | alpha-Synuclein -- genetics | alpha-Synuclein -- metabolism | Lewy Bodies -- pathology | Neuroprotective Agents -- therapeutic use | Parkinson Disease -- etiology | Parkinson Disease -- genetics | Parkinson Disease -- metabolism | Parkinson Disease -- therapy | Prion Diseases -- genetics | Prion Diseases -- metabolismOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Parkinson's disease : symptoms and pathology (PD mutations and risk factors) -- Braak staging of Lewy body-related pathology in PD -- The prion-like hypothesis -- Key steps of alpha-synuclein pathology propagation (Release, Uptake, Seeding, Transport) -- In vivo and cell models from different species -- Therapeutic targets: promoting degradation, antibody aided clearance, and preventing seeding of alpha-synuclein -- Parkinson's disease vaccine: first clinical studies.
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Mode of access: World Wide Web.