Mechanisms of DNA repair by recombination [electronic resource] / James E. Haber.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Introduction to human genetics : fundamentals and latest advances: Publisher: London : Henry Stewart Talks, 2009Description: 1 online resource (1 streaming video file (66 min.) : color, sound)Subject(s): Human genetics | Medical genetics | DNA Repair | Genetics, MedicalOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Genome instability in tumor cells -- Mutations -- Loss of heterozygozity -- Repair of chromosome breaks -- Double-strand break repair is essential for life -- Replication stalling and fragile sites -- Programmed DSBs -- Repair of DSBs arising during DNA replication by recombination -- The homologous recombination machinery -- E. coli -- Holliday junctions -- Break-induce replication -- Single strand annealing -- Types of homologous recombination -- Observing DNA repair in real time -- Molecular studies of recombination -- Nonhomologous end-joining (NHEJ) pathways -- Copy number variation -- Gene amplification.
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Mode of access: World Wide Web.