TNF superfamily cytokines and receptors in the healthy and diseased immune system [electronic resource] / Richard M. Siegel.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Cytokines: Publisher: London : Henry Stewart Talks, 2011Description: 1 online resource (1 streaming video file (29 min.) : color, sound)Subject(s): Autoimmunity | B cells -- Immunology | Osteoclasts | T cells -- Immunology | Tumor necrosis factor -- Receptors | Tumor necrosis factor | Cytokines -- immunology | Fas-Associated Death Domain Protein | Gene Expression | Immunity, Innate | Osteoclasts | Receptors, Tumor Necrosis Factor | Signal Transduction | Tumor Necrosis Factor-alphaOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Genomics of the TNF/TNFR superfamily -- TNF/TNFR signaling types -- Various domains of TNFR -- TNF ligands and receptor binding -- Fas and the TNFR family -- Apoptosis through DISC recruitment -- FAS-FADD crystal structure -- Gene expression through TRAF proteins and regulation by dynamic expression of ligands -- Lymph node development -- Innate immunity enhancement -- B & T cells and the TNFR superfamily -- Multiple programmed cell death pathways -- Osteoclast development -- Molecular mechanisms of genetic diseases and defects in the Fas pathway -- Fas intra and extracellular mutations -- Therapeutics and anti-inflammatory uses of TNF superfamily blockade.
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Mode of access: World Wide Web.