The molecular biology of the inositol trisphosphate receptor [electronic resource] / Randen Patterson.
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FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Calcium signaling I: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (47 min.) : color, sound)Other title: Molecular biology of the InsP3 receptorSubject(s): Calcium Signaling | Inositol 1,4,5-Trisphosphate ReceptorsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Activation of the IP3-receptor (IP3R), a major endoplasmic Calcium release channel in many cells, is activated by the second messenger inositol 1,4,5-trisphosphate (IP3) -- The IP3R is unique in that it can integrate signals from numerous cellular pathways via a myriad of inputs which include nucleotide binding, phosphorylation, Calcium binding and protein-protein interactions -- A diverse range of cellular functions are modulated by the IP3R including contraction/excitation, secretion, gene expression, cell cycle, apoptosis and cellular growth -- The nodal properties of the IP3R and the mechanisms by which this occurs.
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Mode of access: World Wide Web.