Regulation of synaptic plasticity by astroglia [electronic resource] / Dmitri Rusakov.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Physiology and pathophysiology of neuroglia: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (23 min.) : color, sound)Subject(s): Astrocytes | Cellular signal transduction | Astrocytes -- physiology | Brain -- physiology | Neuronal Plasticity -- physiology | Signal Transduction -- physiology | Synapses -- physiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Astroglia are the most abundant type of glial cells -- Their role has recently emerged as an active contributor to neural function -- The underlying mechanisms remain poorly understood -- Astrocytes release D-serine in a Ca2+ dependent manner -- Interference with this release reduces activation of synaptic NMDA receptors -- This in turn could severely impair induction of long-term synaptic potentiation -- Astroglia thus may play a fundamental role in mechanisms of memory formation in the brain.
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Mode of access: World Wide Web.