Mechanistic aspects and therapeutic applications of RNAi [electronic resource] / John J. Rossi.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. RNA interference : principles and applications: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (44 min.) : color, sound)Subject(s): Antiviral agents | Genetic vectors | HIV infections -- Gene therapy | Lentiviruses | Small interfering RNA -- Therapeutic use | Gene Transfer Techniques | Genetic Therapy | HIV Infections -- therapy | Ribonuclease III | RNA Interference | RNA, Small Interfering -- therapeutic useOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: RNAi mechanisms -- RNAi and HIV infection -- Lentiviral vector-mediated transduction of stem cells and T-cells -- Gene therapy based treatment of HIV-1 -- HIV mutants that abrogate RNAi -- Multiplexing different siRNAs and siRNAs with other antiviral RNAs to minimize viral resistance -- An HIV Tat inducible shRNA expression system -- Multiplexing shRNA with dominant negative M10 protein inhibition of HIV.
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Mode of access: World Wide Web.