Herpes simplex virus and varicella-zoster virus Helicase-Primase inhibitors [electronic resource] / Hugh J. Field.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Antivirals: Publisher: London : Henry Stewart Talks, 2011Description: 1 online resource (1 streaming video file (35 min.) : color, sound)Subject(s): Antiviral agents | Herpes simplex virus -- Effect of drugs on | Herpesvirus diseases | Antiviral Agents -- pharmacology | DNA Helicases -- antagonists & inhibitors | DNA Primase -- antagonists & inhibitors | Herpes Simplex -- drug effects | Herpesvirus 3, Human -- drug effectsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Herpesvirus infections in man -- Diseases caused by alphaherpesvirus, HSV and VZV -- Immunocompromised hosts -- Infection, latency and reactivation -- Morphology of herpesvirus virion -- Productive replication cycle -- The herpesvirus genome -- HSV and VZV antiviral therapy -- Nucleoside analogue therapy -- Historical prospective -- Genes coding for proteins targeted by antivirals -- Inhibitors of DNA synthesis -- A new target -- HSV helicase-primase complex -- Clinical potential of Helicase primase inhibitors (HPIs) -- Studying HPI in vivo -- Antiviral efficacy -- Dose response -- The effects of HPI on HSV latency -- The development of HPI antiviral drug resistance -- HPI resistant mutants growth and pathogenicity.
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Mode of access: World Wide Web.