Novel immunotherapeutic proteins [electronic resource] : immunoligand / Terry B. Strom, Xin Xiao Zheng.
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FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (36 min.) : color, sound)Subject(s): Antibodies, Monoclonal -- therapeutic use | Recombinant Fusion ProteinsOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
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Contents: Potential advantages of mAB -- Challenges for mAB -- Antibody based therapeutic proteins -- Attributes of immunoligands -- Creation of Ig-based fusion proteins -- Non-cytolytic IL-2/Fc fusion protein -- Vaccine trial design -- Creation of cytolytic IL-15R antagonist fusion protein -- Application of immunoligand: immunogen for mAB production, to stain the cognate ligand, to identify cell surface cognate ligands via immunoprecipitation, to create long lived proteins to test the function of the targeting ligand in vivo and to modulate immune responses -- Challenges for immunoligands.
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Mode of access: World Wide Web.