Experimental therapies in Alzheimer's disease [electronic resource] : the development and use of mouse models / David Westaway.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Neurodegenerative diseases : fundamentals, research methods, latest advances: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Other title: Experimental therapies in Alzheimer's disease : use of mouse modelsSubject(s): Alzheimer Disease | Disease Models, Animal | Neurodegenerative DiseasesOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Animal models and AD research -- Role in identifying pathological pathways, biomarkers and candidate therapies -- Design of models and associated technical parameters -- Process of transgenesis -- Developing mouse models for beta-amyloid precursor protein mutations -- TgCRND8 mice -- Transgenic approaches for investigating Tau mutations -- Exploring environmental modifiers of beta-amyloid pathobiology -- Candidate chemical risk-factor for sporadic AD -- Potential of ''smart'' beta-amyloid-directed interventions.
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Mode of access: World Wide Web.