DNA methylation changes in aging cells and tissues [electronic resource] / Jean-Pierre Issa.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. DNA methylation: Publisher: London : Henry Stewart Talks, 2011Description: 1 online resource (1 streaming video file (54 min.) : color, sound)Subject(s): Aging | Cell Aging | DNA MethylationOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Epigenetics -- Phenotypic variation -- DNA methylation -- Promoter CpG & Non CpG islands -- The methylome -- DNA methylation changes in aging -- Hypermethylation and silencing -- Methylation in normal colon vs. age -- Microarray analysis of aging human colon -- Methylation in aging human prostate -- Methylation vs. age in human right atrium -- MCAM analysis of aging mouse colon -- Pyro analysis of aging mouse colon -- Age related methylation along the GI tract -- Epigenetic mosaicism -- Human carcinogenesis as an epigenetic disease -- Changes in tissue function -- Tissue function consequences of DNA methylation changes in aging -- Epigenetic variation in human colon -- Susceptibility to DNA hypermethylation -- DNA hypermethylation and retrotransposons -- Genome-wide analysis of methylation proneness -- Genome architecture and the prediction of hypermethylation -- Repeat element distribution and age-related methylation -- Polycomb targets and hypermethylated genes in aging.
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Mode of access: World Wide Web.