Extracellular domain structures from calcium-sensing and GABA(B) receptors [electronic resource] / Qing R. Fan.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (36 min.) : color, sound)Subject(s): Amino acids -- Receptors | Calcium -- Receptors | Cellular signal transduction | G proteins -- Receptors | Binding Sites | GABA-B Receptor Agonists | GABA-B Receptor Antagonists | Protein Conformation | Receptors, Calcium-Sensing -- chemistry | Receptors, Calcium-Sensing -- metabolism | Receptors, GABA-B -- chemistry | Receptors, GABA-B -- metabolism | Receptors, G-Protein-CoupledOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Crystal structures of human GABA(B) receptor extracellular domain in multiple functional states -- Agonist vs. antagonist recognition -- Identification of novel heterodimer interface associated with receptor activation -- Crystal structures of human CaSR in the inactive and active conformations -- Discovery of L-amino acids as orthosteric agonists of CaSR -- Identification of Ca2+ and PO43 binding sites in CaSR -- Universal activation mechanism of class C GPCRs.
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Mode of access: World Wide Web.