Activation of PTK receptors in solid human tumors [electronic resource] / Marco A. Pierotti.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (50 min.) : color, sound)Other title: Activation of Protein Tyrosine Kinase receptors in solid human tumours | Activation of PTK receptors in solid human tumorsSubject(s): Cellular signal transduction | Neoplasms | Receptor Protein-Tyrosine Kinases | Signal TransductionOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: The human kinome -- Role of tyrosine kinases in cancer -- Mechanisms of activation of RTKs in physiological and pathological conditions -- Autocrine Loop -- The dermatofibrosarcoma protuberans model -- Gene Amplification -- the breast cancer model -- Mutation -- The EGFR and lung cancer model -- The Ret and multiple endocrine type 2 syndrom model -- Gene rearrangment -- The RET and TRK in papillary thyroid carcinoma model -- Thyrosine Kinases and therapeutic targets -- The Gleevec paradigm -- The EGFR inhibitors a new paradigm.
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Mode of access: World Wide Web.