The ERK1/2 MAPK cascade [electronic resource] / Melanie H. Cobb.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (29 min.) : color, sound)Subject(s): Cellular signal transduction | Mitogen-activated protein kinases | MAP Kinase Signaling System | Mitogen-Activated Protein Kinase 1 -- metabolism | Mitogen-Activated Protein Kinase 3 -- metabolismOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: MAPK cascade paradigm -- Properties of the MAPK cascade -- ERK1/2 in disease and development -- Activation of the MAPK cascade -- Structure and motifs in the cascade -- Generating specificity in MAPK cascades -- Docking mechanisms -- MAPK scaffolds -- Feedback mechanisms and pathway interactions -- Regulation of the localization of ERK1/2 -- MAPKs and transcription.
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Mode of access: World Wide Web.