The Eph receptor family [electronic resource] / Elena B. Pasquale.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (36 min.) : color, sound)Subject(s): Cellular signal transduction | Ephrins | Receptor Protein-Tyrosine Kinases | Receptors, Eph Family | Signal TransductionOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Members of the Eph receptor and ephrin ligand families and specificity of binding interactions -- Domain structure of Eph receptors and ephrins -- Eph receptor-ephrin interactions -- Dimerization, tetramerization and further clustering in Eph-ephrin signaling -- Tyrosine phosphorylation in Eph-ephrin activation -- Modes of signal termination -- Eph-ephrin signaling pathways affecting the actin cytoskeleton and cell adhesion: Cell repulsion versus adhesion/attraction, pathways that are activated downstream of Eph receptors -- Main Eph effects on cell behavior: shaping and positioning cellular processes and cell migration -- Eph receptors in topographic mapping in the visual system -- Eph receptors in the organization of axonal projections -- Eph receptors in angiogenesis and lymphangiogenesis -- Eph receptors in stem cell proliferation and differentiation -- Eph receptors in cancer -- Eph receptors as drug targets.
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Mode of access: World Wide Web.