RTKs activate the ERK 1/2 MAPK cascade [electronic resource] / Melanie H. Cobb.

By: Cobb, Melanie H [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (49 min.) : color, sound)Other title: Receptor Protein-Tyrosine Kinases activate the Extracellular Signal-Regulated MAP Kinases cascadeSubject(s): Receptor Protein-Tyrosine Kinases | Signal TransductionOnline resources: Click here to access online | Series
Contents:
Contents: Regulation of the MAPK pathway by receptor tyrosine kinases through Ras -- MAPK cascade paradigm -- Regulatory properties of kinase cascade components -- MAPK structure -- Generating specificity in MAPK cascades -- Docking mechanisms -- MAPK scaffolds -- Feedback mechanisms and pathway interactions -- Regulation of the localization of ERK1/2 -- Functional versatility of MAPK pathways.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: Regulation of the MAPK pathway by receptor tyrosine kinases through Ras -- MAPK cascade paradigm -- Regulatory properties of kinase cascade components -- MAPK structure -- Generating specificity in MAPK cascades -- Docking mechanisms -- MAPK scaffolds -- Feedback mechanisms and pathway interactions -- Regulation of the localization of ERK1/2 -- Functional versatility of MAPK pathways.

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