Modifications of pyruvate handling in health and disease [electronic resource] / Mary Sugden.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein epidemiology: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (36 min.) : color, sound)Subject(s): Protein Conformation | Proteins | Pyruvic AcidOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Potential metabolic fates of pyruvate -- Lactate transport -- Role of pyruvate dehydrogenase complex (PDC) -- Regulation of PDC -- Mechanisms of activation of PDC by pyruvate dehydrogenase phosphatases -- Pyruvate dehydrogenase kinase (PDK) expression and regulation -- Multi-site phosphorylation -- Transcription factors regulating PDK4 expression -- Anaplerosis and cataplerosis -- Pyruvate carboxylase -- Insulin secretion and action -- Glucose/fatty-acid cycle -- Consequences of PDK4 upregulation -- Disorders of pyruvate handling.
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Mode of access: World Wide Web.