RNAi for neurological diseases [electronic resource] / Beverly L. Davidson.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Gene transfer and gene therapy: ; Henry Stewart talksBiomedical & life sciences collection. RNA interference : principles and applications: Publisher: London : Henry Stewart Talks, 2014Description: 1 online resource (1 streaming video file (48 min.) : color, sound)Subject(s): Gene therapy | Genetic vectors -- Therapeutic use | Huntington's disease | Nervous system -- Diseases -- Gene therapy | Nervous system -- Diseases -- Genetic aspects | Small interfering RNA -- Therapeutic use | Gene Transfer Techniques | Genetic Therapy -- methods | Genetic Vectors -- therapeutic use | Huntington Disease -- therapy | MicroRNAs -- therapeutic use | Nervous System Diseases -- therapy | RNA Interference | RNA, Small Interfering -- therapeutic useOnline resources: Click here to access online | Series (RNA interference) | Series (Gene transfer and gene therapy) Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Repeat expansion diseases -- Polyglutamine (polyQ) repeat diseases -- Huntington's disease -- Vectors for delivering genetic material to brain -- AAVs for delivering RNAi for reducing gene expression -- Artificial miRNAs -- Testing miHD for efficacy -- Off-target silencing -- MRI-guided delivery of AAV into primates -- HTT suppression -- Other gain-of function diseases -- Targeted infusion for broad coverage -- Silencing ataxin-1 -- Nonallele specific silencing: experimental design -- Expression and activity of miSCA1.
Access restricted to subscribers.
Mode of access: World Wide Web.