Endoplasmic reticulum stress in neurodegenerative diseases [electronic resource] / Claudio Soto.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein homeostasis: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (41 min.) : color, sound)Subject(s): Endoplasmic reticulum | Nervous system -- Degeneration | Prion diseases | Protein folding | Endoplasmic Reticulum Stress | Neurodegenerative Diseases | Prion Diseases | Protein Folding | Stress, PhysiologicalOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Neurodegenerative disease -- Misfolded aggregates deposited in the brain -- Research strategy -- Prion diseases -- Two conformations of the prion protein -- Experimental scrapie model in mice -- Upregulation of ER chaperones -- ER-stress and UPR in human CJD -- PrP interaction with ER chaperones in brain -- PrPSc induction of ER-stress and neuronal death -- Calcineurin properties -- A novel treatment for prion diseases.
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Mode of access: World Wide Web.