The epidermal growth factor receptor family [electronic resource] : roles in development and cancer / Nancy Hynes.

By: Hynes, Nancy E [spk]Material type: FilmFilmSeries: Henry Stewart talksBiomedical & life sciences collection. Signal transduction via protein tyrosine kinase receptors : structures, function, regulation, mechanisms and role in disease: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (35 min.) : color, sound)Subject(s): Cellular signal transduction | Neoplasms -- etiology | Receptor Protein-Tyrosine Kinases | Receptor, Epidermal Growth Factor | Receptor, ErbB-2 | Signal TransductionOnline resources: Click here to access online | Series
Contents:
Contents: ERBB receptor/ligand network -- Activation and intracellular signaling -- Developmental roles for ERBB2 containing heterodimers -- ERBB receptor structure -- Molecular alterations of ERBB receptors in cancer -- Targeting ERBB receptors in cancer -- In vivo and in vitro studies describing how ERBB receptor blockade impacts on cancer -- Resistance of cancer cells to ERBB inhibitors.
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Animated audio-visual presentation with synchronized narration.

Title from title frames.

Contents: ERBB receptor/ligand network -- Activation and intracellular signaling -- Developmental roles for ERBB2 containing heterodimers -- ERBB receptor structure -- Molecular alterations of ERBB receptors in cancer -- Targeting ERBB receptors in cancer -- In vivo and in vitro studies describing how ERBB receptor blockade impacts on cancer -- Resistance of cancer cells to ERBB inhibitors.

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