Structure and activation of endothelin ETB receptor by endothelin [electronic resource] / Tomoko Doi.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. G Protein-Coupled Receptors (GPCRs) signaling in health and disease: Publisher: London : Henry Stewart Talks, 2019Description: 1 online resource (1 streaming video file (26 min.) : color, sound)Subject(s): Cellular signal transduction | Endothelins -- Physiological effect | Endothelins -- Receptors | G proteins -- Receptors | Bosentan | Endothelin-1 -- chemistry | Endothelin-1 -- metabolism | Endothelin-1 -- pharmacology | Ligands | Protein Conformation | Receptor, Endothelin B -- chemistry | Receptor, Endothelin B -- metabolism | Receptors, Endothelin | Receptors, G-Protein-Coupled | Signal Transduction | Vasoconstriction -- drug effectsOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Background to endothelin, ET(A) and ET(B) -- Endothelin and peptide GPCR -- Vasoactive and mitogen-like peptide -- Thermostabilization of ET(B) -- Structures of ET-1-bound and bosentan-bound ET(B) receptor -- Ligand recognition and conformational changes of ET(B) for signal transduction.
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Mode of access: World Wide Web.