Network motifs [electronic resource] : basic building blocks of biological networks / Uri Alon.
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FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Protein homeostasis: Publisher: London : Henry Stewart Talks, 2012Description: 1 online resource (1 streaming video file (38 min.) : color, sound)Subject(s): Biological models | Computational biology | Algorithms | Gene Regulatory Networks | Models, Genetic | Systems BiologyOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
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Contents: Complex networks are found throughout biology -- Can we define the basic building blocks of networks? -- Database of direct transcription interactions in E. coli -- Algorithm that finds n-node network motifs -- Feedforward loop (FFL) -- Dynamics of the feed-forward loop system -- The feed-forward loop is a filter for transient signals allowing fast shutdown -- GFP reporter plasmid system for promoter activity -- Response to brief pulses of X is filtered by FFL -- Sign-sensitive filtering by arabinose feed-forward loop -- Single input module (SIM) -- Dense overlapping regulons (DOR) -- Incoherent FFL is a pulse generator -- Network motifs in human organ development -- Network motifs in growth factor signalling -- High-accuracy promoter activity measurements in living cells.
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Mode of access: World Wide Web.