Poxviruses [electronic resource] : Smallpox (variola), Vaccinia and Monkeypox / Paula Traktman.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Viruses and viral diseases : emerging threats to humans and animals: Publisher: London : Henry Stewart Talks, 2007Description: 1 online resource (1 streaming video file (60 min.) : color, sound)Subject(s): Monkeypox | Poxviridae | Risk Factors | Smallpox | Vaccinia | Virus Diseases | VirusesOnline resources: Click here to access online | SeriesAnimated audio-visual presentation with synchronized narration.
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Contents: Poxvirus life cycle: chromosome structure, virion structure and virion entry -- Viral proteins needed for entry and mechanism of entry of EV (enveloped virion) -- Gene expression of EV: early transcription, intermediate and late transcription -- Working model of Poxvirus genome replication -- Morphogenesis of EV -- Key features of the IV to MV (mature virions) transition -- Poxviruses encode a three-protein complex that generates disulfide bonds in the cytoplasm -- Formation of EEV (extracellular enveloped virions) and EV mediators of cell-to-cell and distal spread -- Poxviruses encode a large array of immunomodulators -- Models for the study of Poxvirus pathogenesis -- Smallpox (Variola virus) and smallpox disease -- Pathogenicity of Variola virus vs. Vaccinia virus -- Official declaration of the eradication of smallpox -- Monkeypox virus -- Antiviral therapy and new vaccines for Poxviruses.
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Mode of access: World Wide Web.