Structural insights into aminoacyl-tRNA delivery by EF-Tu and translocation by EF-G [electronic resource] / Joachim Frank.
Material type:
FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Mechanisms of ribosome function : insights into protein synthesis: Publisher: London : Henry Stewart Talks, 2008Description: 1 online resource (1 streaming video file (27 min.) : color, sound)Subject(s): Protein Biosynthesis | Ribosomal Proteins | RibosomesOnline resources: Click here to access online | Series Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Schematic of elongation cycle -- Role of elongation factors EF-G and EF-Tu -- Molecular mimicry of elongation factors -- Binding positions of factors and tRNA during elongation cycle -- Process of tRNA selection -- Proofreading -- Role of bases A1492 and A1493 -- GTP hydrolysis on EF-Tu -- tRNA as a molecular spring -- Translocation -- Intersubunit ratchet motion -- Induced fit -- FRET studies of ratchet motion -- Hybrid states of tRNA -- Role of GTP hydrolysis in translocation.
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Mode of access: World Wide Web.