Regulation of apoptosis [electronic resource] : lessons from Drosophila and their implications for human health and disease / Hermann Steller.
Material type:![Film](/opac-tmpl/lib/famfamfam/VM.png)
Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Many different signals influence apoptosis -- "Gas" and "brake" model of apoptosis -- Reaper, Hid and Grim -- IAPs and cancer -- Use of Drosophila -- Ubiquitination and apoptosis -- diap1 -- In proliferating tissues, damage induced cell death is compensated by extra growth of the neighboring cells -- Evidence for the "active model" of compensatory proliferation -- Regulation of caspase activation -- Cytochrome c is required for effector caspase activation in Drosophila spermatids -- Cyt-c-d and other apoptosome proteins are required for normal developmental apoptosis in the Drosophila retina -- Generation of Sept4-null mice -- Acquired characteristics of cancer cells.
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Mode of access: World Wide Web.