Urinary proteomics in kidney and cardiovascular disease [electronic resource] / Harald Mischak.
Material type: FilmSeries: Henry Stewart talksBiomedical & life sciences collection. Clinical proteomics: ; Henry Stewart talksBiomedical & life sciences collection. Kidney in health and disease: Publisher: London : Henry Stewart Talks, 2013Description: 1 online resource (1 streaming video file (53 min.) : color, sound)Subject(s): Biochemical markers | Cardiovascular system -- Diseases | Kidneys -- Diseases | Proteomics -- Methodology | Biomarkers | Cardiovascular Diseases | Kidney Diseases | Proteome -- analysis | Proteomics -- methodsOnline resources: Click here to access online | Series (Clinical proteomics) | Series (Kidney in health and disease)Animated audio-visual presentation with synchronized narration.
Title from title frames.
Contents: Omics technologies -- Technology platforms: (2DE-MS, LC-MS-MS, CE/MS) -- Clinical proteomics -- Precision as a function of no. of markers -- Human urinary LMW proteome database -- Requirements for biomarker selection -- How to identify valid proteomic biomarkers -- Effect size estimation and the number of samples -- Erroneous biomarkers -- Classification using different sizes of training sets -- Classification errors -- CKD biomarkers -- Biomarker validation -- Pathophysiological suggestions -- Selected urinary peptides and CKD staging -- Multicentric European PRIORITY trial -- Proteomics of coronary artery disease and of diabetic nephropathy.
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Mode of access: World Wide Web.