TY - ADVS AU - Golan,Itahk TI - CD44 genetic deletion enhances and CD44 antibody targeting attenuates autoimmune inflammation T2 - Autoimmunity : etiology, pathogenesis, clinical manifestation and diagnostic methodologies, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Autoimmune Diseases KW - Autoimmunity KW - Research N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: CD44 and RHAMM (receptor for hyaluronan-mediated motility) are cell adhesion and cell homing receptors -- Cell migration -- Generation of different CD44 isoforms -- RHAMM also supports cell motility and is engaged in intracellular signalling -- Collagen-induced arthritis and type 1 diabetes are CD44-dependent pathologies -- Molecular redundancy -- CD44 targeting by anti-CD44 mAb may eradicate not only malignant cells and destructive inflammatory cells but also CD44-expressing normal cells which are committed to physiological functions; Access restricted to subscribers UR - https://hstalks.com/bs/213/ UR - https://hstalks.com/bs/p/23/ ER -