TY - ADVS AU - Nelson,George TI - The sources of genomic diversity T2 - Using bioinformatics in the exploration of genetic diversity : fundamentals and recent advances, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Computational Biology KW - Genetics KW - Genomics KW - Variation (Genetics) N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The sources of genomic diversity: DNA and mutation, effect of mutations, inheritance, selection and drift -- Environmental diversity -- Natural selection -- Human genomic diversity -- Population growth -- G6PD -- DNA and mutation: point mutations (SNPs) and more complex mutations -- The effect of mutations: insertions or deletions and large chromosomal inversions -- Translation -- Coding mutations -- The fate of mutations -- Neural mutations -- Deleterious mutations -- Radically beneficial mutations: FOXP2 -- Sometimes beneficial/sometimes deleterious mutations: CCR5 delta-32 and Hgb S -- Promoter mutations -- Mutations traveling together: haplotypes; Access restricted to subscribers UR - https://hstalks.com/bs/466/ UR - https://hstalks.com/bs/p/40/ ER -