TY  - ADVS
AU  - Christiani,David C.
TI  - Molecular epidemiology of lung cancer
T2  - Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks,
PY  - 2007///
CY  - London
PB  - Henry Stewart Talks
KW  - Environmental Exposure
KW  - Genes
KW  - Genetic Predisposition to Disease
KW  - Risk Factors
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The influence of host factors on individual susceptibility to tobacco smoke -- The pleiotropic genes that control activation (Phase I) and detoxification (Phase II) of potential carcinogens -- Effects of the metabolism of environmental compounds on the lipophilic properties of a molecule and the introduction of electronegative moieties within the molecule on carcinogenic potential -- Other susceptibility factors related to defects in DNA repair, alterations in tumor suppressor genes and alterations in tumor invasiveness factors -- Polymorphisms in genes and the association of this with lung cancer development -- The role of inherited polymorphisms of genes involved in xenobiotic metabolism, DNA repair and tumor suppression/invasion (alone and in combination) in lung cancer risk, and modification of this risk by environmental factors such as smoking and diet; Access restricted to subscribers
UR  - https://hstalks.com/bs/80/
UR  - https://hstalks.com/bs/p/24/
ER  -