TY - ADVS AU - Newman,Lee S. TI - Genetic susceptibility in granulomatous disorders: chronic beryllium disease and sarcoidosis T2 - Gene-environment interactions : role in the modulation of pulmonary and autoimmune disease risks, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Environmental Exposure KW - Genes KW - Genetic Predisposition to Disease KW - Risk Factors N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Role of genetics x exposure in environmental lung disease -- Granulomatous disorders and immunologic mechanistic basis: berylliosis and sarcoidosis -- Immunogenetics that may apply generally to granulomatous disorders -- Berylliosis: genetic epidemiology studies, functional genomics and gene x environment interaction studies -- Role of exposure vs. genetic basis -- Sarcoidosis: genetic epidemiology studies, attempts at functional genomics and directions for research to use clinical phenotype and genotype information to improve and help direct the search for an unknown causative agent -- Possible implications for other (non-granulomatous) environmental lung disorders; Access restricted to subscribers UR - https://hstalks.com/bs/83/ UR - https://hstalks.com/bs/p/24/ ER -