TY - ADVS AU - Stingl,Julia TI - Genetic determinants of metabolism: clinical applications in psychiatry T2 - Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs, PY - 2007/// CY - London PB - Henry Stewart Talks KW - Mental Disorders KW - drug therapy KW - Metabolism KW - genetics KW - Pharmacogenetics KW - Psychopharmacology KW - Psychotropic Drugs N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Factors that determine psychiatric importance of genetic variants -- Consequences which arise from genotyping -- Drugs are metabolized via the polymorphic cytochrome P450 enzyme CYP2D6 -- Differences in pharmacokinetic parameters for tricyclics, some SSRIs, other antidepressants, typical and some atypical antipsychotic drugs -- Effects on therapeutic efficacy and adverse events -- Indication for genotyping in psychotropic drug treatment -- Future research to close the gap between pharmacogenetic research and clinical practice; Access restricted to subscribers UR - https://hstalks.com/bs/264/ UR - https://hstalks.com/bs/p/35/ ER -