TY - ADVS AU - Serretti,Alessandro TI - Genetic polymorphisms influencing the response of antidepressants T2 - Psychopharmacogenetics : genetic factors influencing the kinetics and dynamics of psychotropic drugs, PY - 2012/// CY - London PB - Henry Stewart Talks KW - Antidepressants KW - Mechanism of action KW - Depression, Mental KW - Chemotherapy KW - Pharmacogenetics KW - Psychopharmacology KW - Serotonin KW - Physiological effect KW - Receptors KW - Antidepressive Agents KW - pharmacology KW - Depressive Disorder KW - drug therapy KW - genetics KW - Neural Networks, Computer KW - Polymorphism, Genetic KW - Receptors, Serotonin KW - Sleep Initiation and Maintenance Disorders KW - Tryptophan Hydroxylase N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Updated version of a talk first published in 2007; Contents: Pharmacogenetic studies in mood disorder -- Candidate genes as possible genetic predictors of antidepressant response efficacy -- Serotonin transporter gene (5-HTTLPR) -- Serotonin receptor 1A (5HT1A-C-1019G) -- G-protein beta3-subunit (Gbeta3-C825T) -- Serotonin receptor 2A (5HT2A -- 102TC) -- Tryptophan hydroxylase gene (TPH-A218C) -- Associations for FKBP5 and other unreplicated gene variants -- Follow up pharmacogenetic studies -- Circadian Locomotor Output Cycles Kaput (CLOCK-T3111C) gene variants are associated with insomnia and other features -- PER 15 variants and mood disorder phenotypes -- Neural networks: the example of 5-HTTLPR and TPH polymorphisms; Access restricted to subscribers UR - https://hstalks.com/bs/267/ UR - https://hstalks.com/bs/p/35/ ER -