TY - ADVS AU - Cantrell,Doreen TI - Serine kinases and T lymphocyte biology T2 - Protein phosphorylation, PY - 2011/// CY - London PB - Henry Stewart Talks KW - Phosphorylation KW - T cells KW - Protein-Serine-Threonine Kinases KW - metabolism KW - T-Lymphocytes N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: T cell development and function -- T cell activation -- Serine kinase networks -- T cell phosphoproteome -- Kinases active in CTL -- Functions of the CTL phosphoproteins -- PKB signal transduction -- PKB/Akt role in CTL -- Inhibition of PKB -- CCR7 and CD62L -- Homing ability in CTL -- PIP3 & PKB activation -- PTEN deletion/down-regulation effect -- PKB phosphorylates Foxo1 and Foxo3A -- Foxo and CD62L & CCR7 expression -- PKB cascade and KLF2 -- PKB controls T cell trafficking via Foxo; Access restricted to subscribers UR - https://hstalks.com/bs/2065/ UR - https://hstalks.com/bs/p/531/ ER -