TY - ADVS AU - Norman,Paul J. TI - Population-specific evolution of natural killer cell diversity T2 - The biomedical & life sciences collection, PY - 2011/// CY - London PB - Henry Stewart Talks KW - Human genetics KW - Variation KW - Killer cells KW - Population genetics KW - Evolution, Molecular KW - Genetic Variation KW - genetics. KW - Genetics, Population KW - Humans KW - Killer Cells N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: NK cell Diversity; KIR and HLA -- Genetic variety of human immune systems -- Natural killer (NK) cell functions -- HLA and KIR polymorphism -- Genetic association with infectious disease -- Pregnancy syndromes -- Maintenance of diversity in populations -- KIR haplotypes, balancing selection, population bottlenecks, human population diversity -- Natural selection and functional variation, cell-free assays, allelic variants with altered specificities -- Extent of Diversity in Populations -- HLA/KIR compound genotypes and immune identity -- Distribution of viable KIR/HLA interactions -- KIR/HLA in Ancient Humans -- Virtual HLA/KIR genotype of Denisova and Neanderthal -- Distribution of ancient human KIR/HLA alleles in modern humans; Access restricted to subscribers UR - https://hstalks.com/bs/2161/ ER -