TY  - ADVS
AU  - Dougan,David A.
TI  - Protein homeostasis in mitochondria: AAA+ chaperones & proteases 
T2  - Protein homeostasis : folding proteins and maintaining the protein-protein interaction networks,
PY  - 2012///
CY  - London
PB  - Henry Stewart Talks
KW  - Homeostasis
KW  - Mitochondria
KW  - Molecular chaperones
KW  - Proteins
KW  - Metabolism.
KW  - metabolism
KW  - Mitochondrial Proteins
KW  - Molecular Chaperones
N1  - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Protein homeostasis in mitochondria -- Mitochondria play an important role in ageing and disease -- Quality control of mitochondria is controlled at three different levels -- Protein quality control (PQC) in mitochondria is maintained by mitochondrial chaperones and AAA+ proteases -- Following proteotoxic stress a specific mitochondrial unfolded protein response (mtUPR) is activated -- The AAA+ protease CLPXP is proposed to play a key role in mtUPR signaling -- A novel mtCLPX interacting protein that modulates the activity of mtCLPXP both in vitro and in vivo has been identified; Access restricted to subscribers
UR  - https://hstalks.com/bs/2229/
UR  - https://hstalks.com/bs/p/641/
ER  -