TY - ADVS AU - Babu,M.Madan TI - Structure, evolution and dynamics of transcriptional regulatory networks T2 - Protein homeostasis : folding proteins and maintaining the protein-protein interaction networks, PY - 2012/// CY - London PB - Henry Stewart Talks KW - Biological models KW - Genetic transcription KW - Regulation KW - Gene Expression Regulation KW - Gene Regulatory Networks KW - Genomics KW - methods KW - Transcription, Genetic N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Regulatory genomics and systems biology -- Transcriptional networks -- Network motifs -- Scale-free networks -- How transcriptional networks evolve -- Mechanisms for the creation of new genes -- Gene duplication and network growth -- Evolution of local network structure -- Gene regulatory network and expression data -- Back-tracking method to find active sub-networks -Temporal dynamics of local & global structure -- Topological properties -- Dynamic properties -- Hierarchical organisation in networks & of regulatory proteins -- Noise in protein levels -- Non-genetic variation -- Phenotypic variability in fluctuating environments -- Differential cell-fate outcome -- Node dynamics; Access restricted to subscribers UR - https://hstalks.com/bs/2218/ UR - https://hstalks.com/bs/p/641/ ER -