TY - ADVS AU - Hanisch,Uwe-Karsten TI - Physiology and pathophysiology of microglia T2 - Physiology and pathophysiology of neuroglia : roles in health and disease, PY - 2012/// CY - London PB - Henry Stewart Talks KW - Central nervous system KW - Pathophysiology KW - Microglia KW - Central Nervous System KW - immunology KW - physiopathology KW - Immunity, Innate KW - pathology KW - physiology N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Physiology and pathophysiology of microglia -- Microglia -- resident innate immune cells of the CNS -- Approaches to the study of microglia -- Developmental origin and functions -- Developmental contributions and consequences of malfunction -- The concept of 'resting' microglia -- functions in the healthy adult CNS -- Tissue surveillance and synaptic nursing as house-keeping duties -- The concept of microglial 'activation' -- transformation to distinct activity states -- The concept of detrimental microglia -- Activation signals and response diversity -- Macrophages and microglia: diversity in response behaviour -- Elements of the microglial response repertoire -- Response dynamics -- Microglial phenotypes associated with phagocytosis -- Contributions of microglia in neurodegenerative diseases; Access restricted to subscribers UR - https://hstalks.com/bs/2355/ UR - https://hstalks.com/bs/p/584/ ER -