TY - ADVS AU - Trebak,Mohamed TI - Store-operated Ca2+ entry and vascular smooth muscle remodeling T2 - Calcium signaling II : calcium and disease, PY - 2012/// CY - London PB - Henry Stewart Talks KW - Calcium channels KW - Calcium KW - Metabolism KW - Cellular signal transduction KW - Vascular smooth muscle KW - Physiology KW - Calcium Channels KW - physiology KW - Calcium Signaling KW - metabolism KW - Muscle, Smooth, Vascular N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: Store-operated Ca2+ entry (SOCE) -- Measuring SOCE -- The whole-cell current mediated by SOCE, ICRAC -- The molecular players and mechanisms of activation of SOCE -- Vascular Smooth muscle cell (VSMC) remodeling -- VSMC organization and function -- VSMC contribution to vascular disease -- VSMC remodeling in restenosis -- VSMC remodeling and expression of ion channel/transporters -- SOCE and VSMC remodeling -- Role of STIM1 and Orai1 in VSMC SOCE and ICRAC -- STIM1 and Orai1 upregulation in VSMC from injured rat carotid vessels -- Role of STIM1 and Orai1 in driving VSMC remodeling in vivo -- STIM1- and Orai1-mediated SOCE and NFAT activity in VSMC -- STIM1 and Orai1 and SOCE in response to the potent proliferative and migratory agonist, PDGF; Access restricted to subscribers UR - https://hstalks.com/bs/2410/ UR - https://hstalks.com/bs/p/683/ ER -