TY - ADVS AU - Lambrecht,Bart N. TI - Dendritic cells in asthma T2 - Advances in asthma : new mechanisms, management strategies and treatments, PY - 2013/// CY - London PB - Henry Stewart Talks KW - Asthma KW - Immunological aspects KW - Dendritic cells KW - immunology KW - pathology KW - Dendritic Cells N1 - Animated audio-visual presentation with synchronized narration; Title from title frames; Contents: The global immune response of the lungs -- Dendritic cells (DCs): localisation, trafficking, probing for antigen, activation, behaviour in airways during asthma and inflammation -- Controlling responsiveness to the node T cell area & Immunological synapse formation -- Peptide presentation by MHC class II molecules -- Cascade of costimulatory events -- Th2 lymphocytes role in airway inflammation -- Targeting DCs -- Allergen exposure activation -- Epithelial vs. DC expression of TLR4 -- Metabolic alterations -- Uric acid and antigen sensitisation in mice -- DC depletion -- Basement membrane thickening in asthma -- Model of chronic airway remodelling in the lungs -- Collagen deposition & antigen uptake/recognition -- Presentation of neoantigen; Access restricted to subscribers UR - https://hstalks.com/bs/2633/ UR - https://hstalks.com/bs/p/640/ ER -